Management of progressive genu varum in a patient with Dyggve-Melchior-Clausen syndrome
نویسندگان
چکیده
We describe the orthopaedic management of progressive genu varum in a child who manifested the full phenotypic characterization of Dyggve-Melchior-Clausen syndrome.
منابع مشابه
Dyggve melchior clausen syndrome.
Dyggve Melchior Clausen syndrome is a rare autosomal recessive disorder, characterized by progressive spondylo epi metaphyseal dysplasia associated with mental retardation. The clinical and radiological findings resembles Morquio disease at the onset of condition, which may hinder its diagnosis. Two siblings with chatacteristic clinical (progressive postnatal dwarfism and mental retardation) an...
متن کاملDyggve-Melchior-Clausen syndrome.
Dyggve-Melchior-Clausen syndrome (DMC) is a rare, dwarfing, skeletal dysplasia characterised by a coarse facies, bulky jaws, short trunk, and barrel chest. Significant radiographical changes include platyspondyly and dysplasia of the epiphyses and metaphyses of the proximal limb bones. Dislocation of the hips and malalignment of the spine and knees are variable features. Inheritance is autosoma...
متن کاملDyggve-Melchior-Clausen syndrome without mental retardation (Smith-McCort dysplasia): morphological findings in the growth plate of the iliac crest.
Dyggve-Melchior-Clausen syndrome without mental retardation (Smith-McCort dysplasia) (SM) has clinical and radiographic findings similar to those of Dyggve-Melchior-Clausen syndrome (DMC) except for mental retardation. Iliac crest biopsies from two patients with SM were examined. The lace-like appearance of the iliac crests, which is a characteristic radiological sign of SM and DMC, was caused ...
متن کاملHomozygosity mapping of a Dyggve-Melchior-Clausen syndrome gene to chromosome 18q21.1.
Dyggve-Melchior-Clausen syndrome (DMC) is an autosomal recessive condition characterised by short trunk dwarfism, scoliosis, microcephaly, coarse facies, mental retardation, and characteristic radiological features. X rays show platyspondyly with double vertebral hump, epiphyseal dysplasia, irregular metaphyses, and a characteristic lacy appearance of the iliac crests. Electron microscopy of ch...
متن کاملMucopolysaccharidosis: Paper Electrophoretic and Infra-red Analysis of the Urine in Gargoylism and Morquio-ullrich's Disease.
Urinary excretion of acid mucopolysaccharides of varying composition and amount has been found in a number of rare diseases, mainly affecting the connective tissues. Recently excretion of chondroitin sulphate and hyaluronic acid in the urine of a patient with mastocytosis has been described by Asboe-Hansen and Clausen (1963). Evidence of the presence of acid mucopolysaccharides in different org...
متن کامل